全球首个！厦大牵头研发的“鼻喷疫苗”获批紧急使用！
<section data-mpa-powered-by="yiban.io"><mp-common-profile class="js_uneditable custom_select_card mp_profile_iframe" data-pluginname="mpprofile" data-weui-theme="light" data-id="MzAwMzY1NTQ4Mw==" data-headimg="https://www.fqlook.cn/plugin.php?id=wcn_editor:wx_img&url=http://mmbiz.qpic.cn/mmbiz_png/wnHzB2hPONq5Bjgb651vpmkrj7AH7bfLicicmo4Zk54rAYPqyOfhok2TD4LnTRbH5wRK23O11o922k93GvlZ2TSQ/0?wx_fmt=png" data-nickname="壹福清" data-alias="efuqing" data-signature="壹福清是福清官方新闻平台，我们每天推送福清最权威信息。" data-from="0" data-is_biz_ban="0"></mp-common-profile></section><p></p><section><section style="margin-bottom: unset;"><p style="margin-bottom: 0px;outline: 0px;text-align: center;visibility: visible;line-height: 2em;"><span style="outline: 0px;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);visibility: visible;letter-spacing: 2px;">12月2日</span></p><section data-role="outer" label="edit by 135editor" style="margin-bottom: 0px;outline: 0px;visibility: visible;"><section data-role="paragraph" style="outline: 0px;visibility: visible;"><section style="margin-bottom: 25px;outline: 0px;visibility: visible;"><section style="padding-right: 5px;padding-left: 5px;outline: 0px;text-align: center;color: rgb(62, 62, 62);line-height: 2;visibility: visible;"><p style="outline: 0px;visibility: visible;line-height: 2em;"><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);visibility: visible;letter-spacing: 2px;">经国家卫生健康委提出建议</span></p><p style="outline: 0px;visibility: visible;line-height: 2em;"><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);visibility: visible;letter-spacing: 2px;">国家药品监督管理局组织论证同意</span></p><p style="outline: 0px;visibility: visible;line-height: 2em;"><span style="outline: 0px;font-size: 16px;color: rgb(86, 86, 86);visibility: visible;letter-spacing: 2px;"><span style="font-size: 16px;color: rgb(86, 86, 86);outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;visibility: visible;">由福建省科技厅</span><span style="font-size: 16px;color: rgb(86, 86, 86);outline: 0px;font-family: Helvetica, Arial, sans-serif;visibility: visible;">立项支持的</span></span></p><p style="outline: 0px;visibility: visible;line-height: 2em;"><span style="outline: 0px;font-size: 16px;color: rgb(0, 122, 170);visibility: visible;letter-spacing: 2px;"><strong style="outline: 0px;visibility: visible;"><span style="font-size: 16px;color: rgb(0, 122, 170);outline: 0px;font-family: Helvetica, Arial, sans-serif;visibility: visible;">疫情防控应急科研攻关成果——</span></strong></span></p><p style="outline: 0px;visibility: visible;line-height: 2em;"><span style="outline: 0px;font-size: 16px;color: rgb(0, 122, 170);visibility: visible;letter-spacing: 2px;"><strong style="outline: 0px;visibility: visible;"><span style="font-size: 16px;color: rgb(0, 122, 170);outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;visibility: visible;">鼻喷流感病毒载体新冠肺炎疫苗</span></strong></span></p><p style="outline: 0px;visibility: visible;line-height: 2em;"><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);visibility: visible;letter-spacing: 2px;">（以下简称“鼻喷疫苗”）</span></p><p style="outline: 0px;visibility: visible;line-height: 2em;"><span style="outline: 0px;font-size: 16px;color: rgb(0, 122, 170);visibility: visible;letter-spacing: 2px;"><strong style="outline: 0px;visibility: visible;"><span style="font-size: 16px;color: rgb(0, 122, 170);outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;visibility: visible;">获批在中国国内紧急使用！</span></strong></span></p><section style="outline: 0px;visibility: visible;line-height: 2em;"><span style="outline: 0px;font-size: 16px;color: rgb(86, 86, 86);visibility: visible;letter-spacing: 2px;"><strong style="outline: 0px;visibility: visible;"><span style="font-size: 16px;color: rgb(86, 86, 86);outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;visibility: visible;"><section>//www.fqlook.cn/plugin.php?id=wcn_editor:player&url=https%3A%2F%2Fmp.weixin.qq.com%2Fmp%2Freadtemplate%3Ft%3Dpages%2Fvideo_player_tmpl%26action%3Dmpvideo%26auto%3D0%26vid%3Dwxv_2695183702586408961&org=http%3A%2F%2Fmp.weixin.qq.com%2Fs%3F__biz%3DMzAwMzY1NTQ4Mw%3D%3D%26mid%3D2709694810%26idx%3D1%26sn%3De4ba3f2dec13ec1bb76aa2077da43698%26chksm%3Dbf41db0e883652180b3ab03142a191c5fd899fc0274afd2069be5afb8530511a0f1d872c973e</section></span></strong></span></section></section></section><section style="outline: 0px;text-indent: 2em;line-height: 2em;"><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);letter-spacing: 2px;">鼻喷苗采用经特别改造以提高安全性和有效性的双重减毒甲型流感病毒作为载体，插入新冠病毒刺突蛋白RBD基因片段研制而成。</span></section><section style="outline: 0px;text-indent: 2em;line-height: 2em;"><br/></section><section style="outline: 0px;text-indent: 2em;line-height: 2em;"><span style="letter-spacing: 2px;"><span style="outline: 0px;color: rgb(86, 86, 86);font-size: 16px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;">该款“鼻喷疫苗”由厦门大学牵头，联合香港大学、北京万泰公司共同研制，是我国布局新冠疫苗应急攻关的</span><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(0, 122, 170);"><strong style="outline: 0px;">五条技术路线之一</strong></span><span style="outline: 0px;color: rgb(86, 86, 86);font-size: 16px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;">，也是</span><span style="outline: 0px;font-size: 16px;color: rgb(0, 122, 170);"><strong style="outline: 0px;"><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;">全球首个获批进入临床试验</span></strong></span><span style="outline: 0px;color: rgb(86, 86, 86);font-size: 16px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;">的“鼻喷疫苗”。</span></span></section><section style="outline: 0px;line-height: 2em;"><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);letter-spacing: 2px;"><br style="outline: 0px;"/></span></section><section style="outline: 0px;line-height: 2em;"><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);letter-spacing: 2px;"></span></section><section style="outline: 0px;line-height: 2em;"><br/></section><section style="outline: 0px;text-indent: 2em;line-height: 2em;"><span style="letter-spacing: 2px;"><span style="outline: 0px;color: rgb(86, 86, 86);font-size: 16px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;">厦门大学国家传染病诊断试剂与疫苗工程技术研究中心夏宁邵团队介绍，该“鼻喷疫苗”采用流感病毒载体，可在呼吸道诱导多维度保护性免疫应答，其通过</span><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(0, 122, 170);"><strong style="outline: 0px;">鼻腔喷雾方式接种</strong></span><span style="outline: 0px;color: rgb(86, 86, 86);font-size: 16px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;">，可在呼吸道形成</span><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(0, 122, 170);"><strong style="outline: 0px;">预防新冠病毒入侵的第一线免疫屏障</strong></span><span style="outline: 0px;color: rgb(86, 86, 86);font-size: 16px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;">，具有</span><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(0, 122, 170);"><strong style="outline: 0px;">快速起效、持久保护</strong></span><span style="outline: 0px;color: rgb(86, 86, 86);font-size: 16px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;">等特点，对包括奥密克戎在内的各种关切突变株具有突出的广谱保护优势，且</span><span style="outline: 0px;font-size: 16px;color: rgb(0, 122, 170);"><strong style="outline: 0px;"><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;">接种方式便捷无痛，民众接受度更高，有助于大幅提高疫苗加强免疫接种覆盖率</span></strong><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;">。</span></span></span></section><section style="outline: 0px;line-height: 2em;"><br/></section><section style="outline: 0px;text-align: center;line-height: 2em;"><span style="outline: 0px;font-size: 16px;color: rgb(86, 86, 86);letter-spacing: 2px;">那么</span></section><section style="outline: 0px;text-align: center;line-height: 2em;"><span style="outline: 0px;font-size: 16px;color: rgb(0, 122, 170);letter-spacing: 2px;"><strong style="outline: 0px;"><span style="font-size: 16px;color: rgb(0, 122, 170);outline: 0px;font-family: Helvetica, Arial, sans-serif;">“鼻喷疫苗”对哪些人适用呢？</span></strong></span></section><section style="outline: 0px;text-align: center;line-height: 2em;"><span style="outline: 0px;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);letter-spacing: 2px;">一起来看——</span></section><section style="outline: 0px;text-align: center;line-height: 2em;"><span style="outline: 0px;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);letter-spacing: 2px;"><br style="outline: 0px;"/></span></section><section data-tools="135编辑器" data-id="114359" data-color="#0267a6" style="outline: 0px;"><section style="outline: 0px;background-color: rgb(251, 253, 254);transform-style: preserve-3d;line-height: 2em;"><section style="outline: 0px;display: flex;justify-content: space-between;align-items: flex-end;transform: translateZ(10px);"><section style="outline: 0px;width: 20px;height: 20px;background-color: rgb(191, 240, 253);overflow: hidden;"><br style="outline: 0px;"/></section><section style="outline: 0px;width: 20px;height: 20px;background-color: rgb(2, 103, 166);overflow: hidden;"><br style="outline: 0px;"/></section></section></section><section style="margin: -15px 5px;padding: 30px 25px;outline: 0px;background-color: rgb(255, 255, 255);transform: translateZ(12px);"><section data-autoskip="1" style="outline: 0px;line-height: 1.75em;letter-spacing: 1.5px;font-size: 14px;background: transparent;"><section style="outline: 0px;text-indent: 2em;line-height: 2em;"><span style="letter-spacing: 2px;"><span style="outline: 0px;font-size: 16px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;color: rgb(86, 86, 86);">该“鼻喷疫苗”适用于</span><span style="outline: 0px;font-size: 16px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;color: rgb(0, 122, 170);"><strong style="outline: 0px;">18</strong><strong style="outline: 0px;">岁及以上人群，包括未免疫任何新冠疫苗人群，以及既往已接种过1针、2针或3针其他新冠疫苗人群</strong></span><span style="outline: 0px;font-size: 16px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;color: rgb(86, 86, 86);">，均采用0、2 周程序接种两剂。</span></span></section></section></section><section style="margin-top: 20px;margin-right: auto;margin-left: auto;outline: 0px;line-height: 2em;"><section style="outline: 0px;display: flex;justify-content: space-between;align-items: flex-end;transform: translateZ(10px);"><section style="outline: 0px;width: 20px;height: 20px;background-color: rgb(2, 103, 166);overflow: hidden;"><br style="outline: 0px;"/></section><section style="outline: 0px;width: 20px;height: 20px;background-color: rgb(191, 240, 253);overflow: hidden;"><br style="outline: 0px;"/></section></section></section></section><section style="outline: 0px;text-align: center;line-height: 2em;"><br/></section><section style="outline: 0px;text-indent: 2em;line-height: 2em;"><span style="letter-spacing: 2px;"><span style="outline: 0px;color: rgb(86, 86, 86);font-size: 16px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;">数据表明，不论用于无免疫史人群的基础免疫还是有免疫史人群的序贯加强免疫，该“鼻喷疫苗”对于Omicron突变株感染导致的COVID-19均可产生良好的保护效力，</span><span style="outline: 0px;font-size: 16px;color: rgb(0, 122, 170);"><strong style="outline: 0px;"><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;">60岁以上人群保护效力不弱于18-59岁人群</span></strong></span><span style="outline: 0px;color: rgb(86, 86, 86);font-size: 16px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;">，同时，</span><span style="outline: 0px;font-size: 16px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;color: rgb(0, 122, 170);"><strong style="outline: 0px;">具有很好的安全性</strong>。</span></span></section><section style="outline: 0px;text-indent: 2em;line-height: 2em;"><span style="outline: 0px;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);letter-spacing: 2px;"><br style="outline: 0px;"/></span></section><section style="max-inline-size: 100%;cursor: text;color: rgb(0, 0, 0);font-family: 微软雅黑, Microsoft YaHei, sans-serif;caret-color: rgb(255, 0, 0);background-color: rgb(255, 255, 255);text-indent: 2em;line-height: 2em;outline: none 0px !important;"><span style="max-inline-size: 100%;cursor: text;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);letter-spacing: 2px;outline: none 0px !important;">据悉，2020年新冠疫情发生以来，福建省科技厅按照福建省委省政府的决策部署，强化省科研攻关组职能，组建工作专班，单独设置新冠病毒疫苗组，充分调动全省科技资源和各方力量，组织开展新冠疫苗科研攻关。据介绍，福建省第一时间启动了科研攻关快速应急响应机制。2020年疫情初期，省科技厅快速摸排全省传染病防治、病毒检测、疫苗研发等领域优势科研单位、企业和专家，在全国范围内较早启动征集疫情防控应急科研攻关项目，疫苗研发方面重点依托厦门大学国家传染病诊断试剂与疫苗工程技术研究中心夏宁邵团队，从减毒载体疫苗、基因工程重组疫苗两条技术路线开展应急攻关。</span></section><section style="max-inline-size: 100%;cursor: text;color: rgb(0, 0, 0);font-family: 微软雅黑, Microsoft YaHei, sans-serif;caret-color: rgb(255, 0, 0);background-color: rgb(255, 255, 255);text-indent: 2em;line-height: 2em;outline: none 0px !important;"><br/></section><section style="max-inline-size: 100%;cursor: text;color: rgb(0, 0, 0);font-family: 微软雅黑, Microsoft YaHei, sans-serif;caret-color: rgb(255, 0, 0);background-color: rgb(255, 255, 255);text-indent: 2em;line-height: 2em;outline: none 0px !important;"><span style="max-inline-size: 100%;cursor: text;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);letter-spacing: 2px;outline: none 0px !important;">为加快新冠疫苗研发工作、推动产品早日上市，福建省密切跟踪项目进展，全力跟进做好课题立项、临床前研究、申请批件、临床研究、紧急使用等环节服务保障工作。据介绍，该“鼻喷疫苗”于2020年8月27日获得国家药监局颁发的临床试验批件，经过努力，“鼻喷疫苗”陆续完成了国内I期、II期和拓展临床试验，海外Ⅲ期临床试验也于今年10月7日揭盲，研究数据显示，该疫苗对Omicron株导致的症状性感染有良好的保护效果和极好的安全性。</span></section><section style="max-inline-size: 100%;cursor: text;color: rgb(0, 0, 0);font-family: 微软雅黑, Microsoft YaHei, sans-serif;caret-color: rgb(255, 0, 0);background-color: rgb(255, 255, 255);text-indent: 2em;line-height: 2em;outline: none 0px !important;"><br/></section><section style="max-inline-size: 100%;cursor: text;color: rgb(0, 0, 0);font-family: 微软雅黑, Microsoft YaHei, sans-serif;caret-color: rgb(255, 0, 0);background-color: rgb(255, 255, 255);text-indent: 2em;line-height: 2em;outline: none 0px !important;"><span style="max-inline-size: 100%;cursor: text;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);letter-spacing: 2px;outline: none 0px !important;">据悉，福建省科技厅立项支持的另一疫苗项目“新佐剂重组新冠肺炎疫苗”也在加快研制，目前已完成首批试验产品灌装，正在进行攻毒保护试验和临床前安全性评估。</span></section><section style="max-inline-size: 100%;cursor: text;color: rgb(0, 0, 0);font-family: 微软雅黑, Microsoft YaHei, sans-serif;caret-color: rgb(255, 0, 0);background-color: rgb(255, 255, 255);text-indent: 2em;line-height: 2em;outline: none 0px !important;"><br/></section><section style="max-inline-size: 100%;cursor: text;color: rgb(0, 0, 0);font-family: 微软雅黑, Microsoft YaHei, sans-serif;caret-color: rgb(255, 0, 0);background-color: rgb(255, 255, 255);text-indent: 2em;line-height: 2em;outline: none 0px !important;"><span style="max-inline-size: 100%;cursor: text;text-shadow: none;font-family: Helvetica, Arial, sans-serif;font-size: 16px;color: rgb(86, 86, 86);letter-spacing: 2px;outline: none 0px !important;">除疫苗产品外，福建省科技厅正同步推动福建省“广谱抗新冠病毒口服药3CL蛋白酶抑制剂GST-HG171”尽快上市使用，加快高效便携快速“个人核酸居家自测试剂盒”项目投产，加速基于紫外光病毒瞬灭技术的全国首套“紫外光催化复合消杀机”产业化，力争为国家疫情防控贡献更多福建方案与科技力量。</span></section><section style="outline: 0px;"><br/></section></section></section></section><section style="outline: 0px;color: rgb(34, 34, 34);letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: right;caret-color: rgb(34, 34, 34);line-height: 1.5em;font-family: -apple-system, BlinkMacSystemFont, Arial, sans-serif;visibility: visible;"><br/></section></section><p></p><h2 style="margin: 0px 0px 14px;padding: 0px;outline: 0px;font-weight: 400;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word;line-height: 1.4;text-align: left;"><p style="margin: 0px;padding: 0px;outline: 0px;max-width: 100%;letter-spacing: 0.54px;line-height: 2em;font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif;background-color: rgb(255, 255, 255);color: rgb(111, 111, 111);font-size: 14px;text-align: justify;white-space: normal;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;font-weight: 400;orphans: 2;text-indent: 0px;text-transform: none;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-style: initial;text-decoration-color: initial;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;"><span style="margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;color: rgb(136, 136, 136);font-family: 宋体;letter-spacing: 0.54px;">来源 厦门大学 新福建 海博TV</span></p><p style="margin: 0px;padding: 0px;outline: 0px;max-width: 100%;letter-spacing: 0.54px;line-height: 2em;font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif;background-color: rgb(255, 255, 255);color: rgb(111, 111, 111);font-size: 14px;text-align: justify;white-space: normal;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;font-weight: 400;orphans: 2;text-indent: 0px;text-transform: none;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-style: initial;text-decoration-color: initial;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;"><br/></p></h2><link rel="stylesheet" href="//www.fqlook.cn/source/plugin/wcn_editor/public/wcn_editor_fit.css?v134_a8o" id="wcn_editor_css"/> 鼻腔喷雾方式接种，好像很不错的样子{:5_283:}{:5_283:}{:5_283:} “个人核酸居家自测试剂盒”项目，新的发家致富 希望这些产品，能够早发现病毒，早消灭病毒 哇噻{:5_270:}{:5_270:}{:5_270:} 鼻喷流感病毒载体新冠肺炎疫苗 {:5_248:}{:5_248:}{:5_248:}{:5_240:}{:5_240:} 这一届科学工作者们太优秀了{:5_270:} 希望鼻喷可以尽快推广到18岁以下人群，下一针就不用和熊孩子斗智斗勇了 中国共产党万岁！中国人民万岁！
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